Bruce Appel, Ph.D.

Professor of Pediatrics

Diane G. Wallach Chair of Pediatric Stem Cell Biology

Head, Section of Developmental Biology

Bruce obtained his Ph.D. in Developmental Biology with Dr. Shige Sakonju at the University of Utah, received postdoctoral training with Dr. Judith Eisen at the University of Oregon and began his faculty career at Vanderbilt University. He moved to the University of Colorado Anschutz Medical Campus in 2008.

Caleb Doll, Ph.D.

Assistant Research Professor

Caleb received a B.S. in Biological Sciences and a PhD in Neuroscience from Vanderbilt University. During his postdoctoral fellowship, he investigated the development of olfactory learning and memory circuitry in the context of Fragile X syndrome. His current research centers around the role of activity in the development of spinal circuits and the impact of Fragile X syndrome on glial cell biology.

Christina Kearns, M.S.

Lab Manager

Having been with the lab since it opened at CU AMC, Christina handles ordering, compliance, training, repairs, lab meeting  schedules and lab duty assignments AND performs her own research projects focused on neural progenitor specification and myelination.

Alex Hughes

Graduate Student

Neuroscience Program

Alex received a BS in biology and mathematics from Boise State University in 2014. After graduating, she taught math courses as an adjunct in the BSU math department and continued working on her undergraduate research project in Julia Oxford’s lab. In 2015, Alex entered the Neuroscience Graduate Program at the University of Colorado and joined the Appel lab the following year. Her project aims to determine how synaptic communication directs the selection of axons for myelination. To do this, she uses the zebrafish as a model system to express optical tools in specific neurons and myelinating glia to monitor and manipulate synaptic features of this interaction during development. Alex has been funded by a National Science Foundation Graduate Fellowship.

Katie Yergert, M.S.

Graduate Student

Molecular Biology Program

Katie received a B.A. in Forensic Biology from Guilford College and a M.S. in Forensic DNA and Serology from the University of Florida. After working as a Genetic Technologist for a private company, she joined the Appel Lab as a graduate student in the Molecular Biology Program. Currently, Katie is studying how the dynamics of RNA transport and local translation contribute to myelination of axons in vivo. To accomplish this, she is utilizing a variety of techniques to visualize RNA transport and protein synthesis in living zebrafish. Katie has been supported by a T32 Training Grant in Molecular Biology, a RNA Bioscience Initiative Graduate Fellowship and a Bolie Scholar Graduate Fellowship.

Karlie Fedder

Graduate Student

Neuroscience Program

Karlie received a B.A. in Biochemistry from Case Western Reserve University in 2013. Following graduation, she worked as a Research Assistant in the Sabo lab at CWRU before joining the Neuroscience Graduate Program in 2016. In the Appel lab, Karlie is interested in the role of NG2 glia in synapse development. To this end, she utilizes a combination of genetic and pharmacological manipulations of signaling cascades paired with molecular biological and imaging analyses of developing zebrafish.

Kayt Scott

Graduate Student

Cell Biology, Stem Cells and Development Program

Kayt received her B.S. in Cellular, Molecular, and Developmental Biology from Colorado Mesa University in 2016. The fall after graduating she enrolled in the CSD program at CU Anschutz, and shortly after joined the Appel lab. Her research is aimed at understanding the transcriptional networks that regulate developmental timing and fate decisions of oligodendrocyte precursor cells. Outside of the lab, Kayt takes advantage of living in Colorado, often taking weekend fishing and camping trips. 

Sam Bromley-Coolidge

Graduate Student

Neuroscience Program

Description coming soon!

Natalie Carie

Graduate Student

Neuroscience Program

Description coming soon!

Alumni

Hae-Chul Park, Associate Professor

Korea University

 

Jimann Shin, Postdoctoral Fellow

Washington University

 

Andrew Latimer, 

Research Scientist

University of Virginia

 

David Mawdsley, Staff Scientist

Def. Sci. & Tech. Org., Australia

 

Karen Meisch, Associate Professor

Austin Peay University

 

Norio Takada, Assistant Professor

Nara Inst. of Science & Technology

Andy Ravanelli, Research Scientist

Sigma, St. Louis MO

Sarah Kucenas, Associate Professor

University of Virginia

 

Brandon Kirby

 

Randolph Roberts (deceased)

 

Denise Zannino, Science Policy and Communication Analyst in the Office of Legislative and Public Affairs, NSF

 

Julia Snyder, Laboratory Manager

Stowers Institute for Med. Res.

 

Tim Simmons, Lawyer

Denver CO

Laura Hudish, Postdoctoral Fellow

University of Colorado SOM

Emily Mathews, Postdoctoral Fellow

Washington University, St. Louis MO

 

 

Melissa Langworthy, Tech. Writer

SurveyGizmo

 

Macie Walker, Research Assoc.

University of Colorado SOM

 

Jacob Hines, Assistant Professor

Wynona State University

 

Yuying Wang, Research and Development Manager

BGI, Shenzhen, China

 

Alex Blasky, Global Market Development Manager, ThermoFisher

 

Anita Quintana, Assistant Professor

University of Texas El Paso